Zakros (Greek: Ζάκρος) is a site on the eastern coast of the island of Crete, Greece, containing ruins from the Minoan civilization. The site is often known to archaeologists as Zakro or Kato Zakro.

It is believed to have been one of the four main administrative centers of the Minoans, and its protected harbor and strategic location made it an important commercial hub for trade to the east.

The town was dominated by the Palace of Zakro, originally built around 1900 BC, rebuilt around 1600 BC, and destroyed around 1450 BC along with the other major centers of Minoan civilization. Extensive ruins of the palace remain, and are a popular tourist destination